Disodium etidronate in hypercalcaemia due to immobilisation.

Immobilisation hypercalcaemia complicating polyneuropathy in adolescent boys.

Two boys who were immobilised with peripheral neuropathy developed hypercalcaemia. It is suggested that hypercalcaemia aggravated the muscle weakness as well as producing systemic upset. The hypercalcaemia was controlled with corticosteroids which had to be continued over several months. A satisfactory remission of the disease occurred in both cases. The hypercalcaemia was attributed to immobil...

Influence of disodium etidronate on Paget's disease of bone.

The use of agents that decrease bone resorption, notably the calcitonins, diphosphonates and mithramycin, has been shown to result in symptomatic and/or biochemical improvement in patients with Paget's disease of bone (osteitis deformans). The effects of short-term (6 months), low-dose (5 mg/kg body mass/d) etidronate disodium, a diphosphonate compound at present subject to registration in this...

Immobilisation hypercalcaemia in adults and treatment with clodronate.

Recurring 'red eyes' due to seasonal hypercalcaemia.

Recurrent hypercalcaemia associated with hypersensitivity to ultra violet light occurring in a patient who had had clinical sarcoidosis 14 years previously. Hypercalcaemia in sarcoidosis is a well known association, but it is less often realized that this hypercalcaemia may undergo seasonal variation (Taylor, Lynch and Wyser, 1963). The following case report describes recurring seasonal symptom...

Immobilization hypercalcaemia due to low bone formation

A young man developed acute renal failure and hypercalcaemia following severe burns. The hypercalcaemia was initially controlled by haemodialysis, but it persisted after return of renal function. Plasma PTH was inappropriately elevated, but the nephrogenous cyclic adenosine monophosphate level was low; thus the PTH was probably not biologically active, and may have been artefactually elevated b...